Description

17,21-[(Butylboranediyl)Bis(Oxy)]Pregn-4-Ene-3,20-Dione is a high-purity, synthetic steroid derivative with a unique boron-containing protecting group. This compound is a critical intermediate in the advanced synthesis of complex pharmaceutical agents, particularly in the development of novel corticosteroids and other therapeutic steroids. It is primarily required by research institutions and pharmaceutical manufacturers engaged in process chemistry, medicinal chemistry, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid drugs and other steroid-based therapeutics.
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates targeting inflammatory pathways and hormonal receptors.
• Process Development & Scale-Up: Serves as a standardized intermediate for optimizing synthetic routes and scaling production from lab to pilot plant.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid APIs.
• Academic Research: Utilized in university and institutional research to study steroid chemistry, protecting group strategies, and boron chemistry applications.
• Biochemical Studies: Investigated for its interaction with specific enzymes and receptors in biochemical assay systems.

Basic Information

Product Name	17,21-[(Butylboranediyl)Bis(Oxy)]Pregn-4-Ene-3,20-Dione
CAS No.	30888-54-1
Molecular Formula	C₂₉H₄₃BO₄
Molecular Weight	466.46 g/mol
Synonyms	17,21-[(Butylboranediyl)bis(oxy)]pregn-4-ene-3,20-dione; 17,21-O-(Butylboranediyl)-11-deoxycortisol; 11-Deoxycortisol 17,21-butylboronate; Pregn-4-ene-3,20-dione, 17,21-[(butylboranediyl)bis(oxy)]-; 17,21-Butylboronate of 11-Deoxycortisol; Cortodoxone 17,21-butylboronate; Reichstein's Substance S 17,21-butylboronate
EINECS	Contact for details

Quality Control

Our 17,21-[(Butylboranediyl)Bis(Oxy)]Pregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.