Description

17,21-[(tert-Butylboranediyl)Bis(Oxy)]Pregn-4-Ene-3,20-Dione CAS NO 30888-53-0 is a high-purity, synthetic steroid derivative featuring a unique tert-butylboranediyl bis(oxy) protecting group. This compound is a critical advanced intermediate in the synthesis of complex steroid-based pharmaceuticals, offering precise control over chemical transformations. It is primarily utilized by research institutions and pharmaceutical manufacturers specializing in the development of novel corticosteroids and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid drugs and other steroid-based active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Used in academic and industrial R&D for studying steroid chemistry, protecting group strategies, and developing new synthetic methodologies.
• Process Chemistry Development: Serves as a standardized intermediate for scaling up and optimizing manufacturing routes for steroid compounds under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	17,21-[(tert-Butylboranediyl)Bis(Oxy)]Pregn-4-Ene-3,20-Dione
CAS No.	30888-53-0
Molecular Formula	C₂₆H₃₉BO₄
Molecular Weight	426.40 g/mol
Synonyms	17,21-O-(tert-Butylboranediyl)prednisolone; 17,21-Di-O-(tert-butylboranediyl)prednisolone; 3,20-Dioxopregn-4-en-17,21-diyl tert-butylboronate; Prednisolone 17,21-bis(tert-butylboronate); 30888-53-0; tert-Butylboronic acid prednisolone ester; Pregn-4-ene-3,20-dione, 17,21-[(1,1-dimethylethyl)boranediyl]bis[oxy]-
EINECS	Contact for details

Quality Control

Our 17,21-[(tert-Butylboranediyl)Bis(Oxy)]Pregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.