Description

(20S)-17,21-[(tert-Butylboranediyl)Bis(Oxy)]-20-Hydroxypregn-4-En-3-One is a high-purity, synthetic steroid derivative featuring a unique boronate ester moiety. This compound is a critical advanced intermediate in the research and development of novel pharmaceutical agents, particularly in the field of endocrinology and anti-inflammatory therapies. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel corticosteroid analogs and other biologically active steroid molecules.
• Research & Development: Used in medicinal chemistry programs to study structure-activity relationships (SAR) and develop new therapeutic candidates targeting hormone receptors.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in biochemical assays to investigate enzyme inhibition, metabolic pathways, and steroid hormone signaling mechanisms.
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses to introduce specific functional groups and stereochemistry found in complex natural products.

Basic Information

Product Name	(20S)-17,21-[(tert-Butylboranediyl)Bis(Oxy)]-20-Hydroxypregn-4-En-3-One
CAS No.	30888-39-2
Molecular Formula	C₂₅H₃₉BO₄
Molecular Weight	414.39 g/mol
Synonyms	20-Hydroxy-17,21-O-(1-methylethylidene)bis[oxy]pregn-4-en-3-one, (20S)-form; 17,21-[(1,1-Dimethylethyl)boranediyl]bis[oxy]-20-hydroxypregn-4-en-3-one; 20-Hydroxy-17,21-O-(tert-butylboranediyl)pregn-4-en-3-one; Steroid boronate ester intermediate; Pregn-4-ene-3,20-dione, 17,21-[(1,1-dimethylethyl)boranediyl]bis[oxy]-, (17α)-; 30888-39-2
EINECS	Contact for details

Quality Control

Our (20S)-17,21-[(tert-Butylboranediyl)Bis(Oxy)]-20-Hydroxypregn-4-En-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and moisture. Allow the sealed container to reach room temperature before opening to prevent condensation and hydrolysis. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.