Description

17,21-[(Phenylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione is a high-purity, specialized steroid derivative featuring a unique phenylboranediyl bisoxy functional group. This compound serves as a critical advanced intermediate in the synthesis of novel pharmaceutical agents and complex bioactive molecules. It is primarily required by research institutions and pharmaceutical development companies focused on endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel corticosteroid analogs and other steroidal pharmaceuticals.
• Biochemical Research: Used in academic and industrial R&D to study enzyme inhibition, receptor binding, and metabolic pathways.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and process optimization for the production of target active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes to investigate specific biological targets and mechanisms.

Basic Information

Product Name	17,21-[(Phenylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione
CAS No.	30888-27-8
Molecular Formula	C28H33BO5
Molecular Weight	460.37 g/mol
Synonyms	5β-Pregnane-3,11,20-trione, 17,21-[(phenylboranediyl)bisoxy]-; 17,21-(Phenylboranediyl)dioxy-5β-pregnane-3,11,20-trione; 17,21-Phenylboranediyl-bis(oxy)-5β-pregnane-3,11,20-trione; Phenylboronic Acid 17,21-Ester of 5β-Pregnane-3,11,20-trione; 30888-27-8; NSC 172112
EINECS	Contact for details

Quality Control

Our 17,21-[(Phenylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.