Description

17,21-[(Butylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione is a high-purity, synthetic steroid derivative with a unique boronate ester functionalization. This compound is a critical advanced intermediate for the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and anti-inflammatory therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for synthesizing targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based drug candidates targeting specific hormone receptors.
• Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new therapeutic entities.
• Process Chemistry: Serves as a pivotal intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	17,21-[(Butylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione
CAS No.	30888-25-6
Molecular Formula	C₂₆H₃₉BO₅
Molecular Weight	442.40 g/mol
Synonyms	5β-Pregnane-3,11,20-trione, 17,21-[(butylboranediyl)bisoxy]-; 17,21-O-(Butylboranediyl)-5β-pregnane-3,11,20-trione; 11-Dehydrocorticosterone 17,21-butylboronate; Corticosterone 17,21-butylboronate derivative; Butylboronic acid 17,21-cyclic ester with 11-dehydrocorticosterone; Steroid boronate ester intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 17,21-[(Butylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccant packs.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.