Description

(20R)-20,21-[(tert-Butylboranediyl)Bis(Oxy)]-5α-Pregnane-3α,11β-Diol CAS NO 30882-71-4 is a high-purity, synthetic steroid derivative featuring a unique boronate ester moiety. This compound is valued as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel corticosteroid analogs and other steroidal drugs.
• Medicinal Chemistry Research: Used as a precursor for structure-activity relationship (SAR) studies to develop new anti-inflammatory or immunosuppressive agents.
• Biochemical Tool Compound: Serves as a probe in enzymatic and receptor-binding studies due to its modified steroidal structure.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(20R)-20,21-[(tert-Butylboranediyl)Bis(Oxy)]-5α-Pregnane-3α,11β-Diol
CAS No.	30882-71-4
Molecular Formula	C₂₅H₄₁BO₄
Molecular Weight	416.41 g/mol
Synonyms	5α-Pregnane-3α,11β-diol, 20,21-[(1,1-dimethylethyl)boranediyl]bis[oxy]-, (20R)-; (20R)-20,21-[(tert-Butylboranediyl)bis(oxy)]-5α-pregnane-3α,11β-diol; 3α,11β-Dihydroxy-5α-pregnan-20,21-diyl tert-butyl boronate; Steroid boronate ester intermediate; Pregnane boronate derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (20R)-20,21-[(tert-Butylboranediyl)Bis(Oxy)]-5α-Pregnane-3α,11β-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and related substances. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.