Description

Pregn-4-En-3-One, 20Beta,21-Dihydroxy-, Cyclic Benzeneboronate is a high-purity steroid derivative and a key protected intermediate in advanced pharmaceutical synthesis. This compound is critical for ensuring the precise chemical transformations required in the production of complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and commercial-scale synthesis of therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of corticosteroid and other steroidal APIs.
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroid-based drug candidates.
• Process Chemistry: Employed in optimizing large-scale manufacturing routes for steroidal drugs, where the boronate protecting group offers specific reactivity advantages.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	Pregn-4-En-3-One, 20Beta,21-Dihydroxy-, Cyclic Benzeneboronate
CAS No.	30882-69-0
Molecular Formula	C28H37BO3
Molecular Weight	432.41 g/mol
Synonyms	20β,21-Dihydroxypregn-4-en-3-one Cyclic Benzeneboronate; 20β,21-Dihydroxy-4-pregnen-3-one Cyclic Phenylboronate; 20β,21-Dihydroxyprogesterone Cyclic Phenylboronate; 20β,21-Dihydroxypregn-4-ene-3,20-dione Cyclic Phenylboronate; 20β-Hydroxycortexolone Cyclic Phenylboronate; Phenylboronic Acid Ester of 20β,21-Dihydroxyprogesterone; 30882-69-0; 20β,21-Dihydroxy-4-pregnene-3-one Cyclic Phenylboronate
EINECS	Contact for details

Quality Control

Our Pregn-4-En-3-One, 20Beta,21-Dihydroxy-, Cyclic Benzeneboronate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.