Description

(20R)-20,21-[(tert-Butylboranediyl)Bis(Oxy)]Pregn-4-En-3-One CAS NO 30882-66-7 is a high-purity, synthetic steroid derivative characterized by a unique boronate ester functionalization at the C-20 and C-21 positions. This compound serves as a critical advanced pharmaceutical intermediate and a versatile research chemical for the development of novel therapeutic agents. It is primarily utilized by R&D laboratories and manufacturing facilities in the pharmaceutical, biotechnology, and fine chemical sectors for process development and synthesis of specialized steroid-based molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel corticosteroid analogs and other bioactive steroid molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new drug candidates.
• Process Chemistry: Serves as a standardized starting material or intermediate in optimizing scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Potential tool compound for studying steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	(20R)-20,21-[(tert-Butylboranediyl)Bis(Oxy)]Pregn-4-En-3-One
CAS No.	30882-66-7
Molecular Formula	C₂₆H₄₁BO₃
Molecular Weight	412.42 g/mol
Synonyms	20,21-(tert-Butylboranediyl)dioxy-20R-pregn-4-en-3-one; 20R-20,21-[(tert-Butylboranediyl)bis(oxy)]pregn-4-en-3-one; (20R)-20,21-[(tert-Butylboranediyl)bis(oxy)]-4-pregnen-3-one; Pregn-4-ene-3-one, 20,21-[(1,1-dimethylethyl)boranediyl]bis(oxy)-, (20R)-; 30882-66-7; tert-Butylboronic acid (20R)-20,21-dihydroxy-pregn-4-en-3-one ester
EINECS	Contact for details

Quality Control

Our (20R)-20,21-[(tert-Butylboranediyl)Bis(Oxy)]Pregn-4-En-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.