Description

(20R)-17,20-[(tert-Butylboranediyl)Bis(Oxy)]-5β-Pregna-3α,11β-Diol CAS NO 30882-63-4 is a high-purity, synthetic steroid derivative characterized by a unique boronic ester functional group. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceutical agents, particularly those targeting hormonal pathways and inflammatory conditions. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic steroids and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel corticosteroid analogs and other bioactive steroid molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Process Chemistry: Serves as a pivotal intermediate in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Tool compound for investigating steroid receptor interactions and metabolic pathways in preclinical studies.

Basic Information

Product Name	(20R)-17,20-[(tert-Butylboranediyl)Bis(Oxy)]-5β-Pregna-3α,11β-Diol
CAS No.	30882-63-4
Molecular Formula	C25H43BO4
Molecular Weight	418.42 g/mol
Synonyms	17,20-[(1,1-Dimethylethyl)boranediyl]bis(oxy)-5β-pregnane-3α,11β-diol, (20R)-; 5β-Pregnane-3α,11β-diol, 17,20-[(1,1-dimethylethyl)boranediyl]bis(oxy)-, (20R)-; tert-Butylboronic acid (20R)-5β-pregnane-3α,11β,17,20-tetrol cyclic 17,20-ester; Steroid boronic ester intermediate; Pregnane boronate derivative.
EINECS	Contact for details

Quality Control

Our (20R)-17,20-[(tert-Butylboranediyl)Bis(Oxy)]-5β-Pregna-3α,11β-Diol is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.