Description

1-(5-Chloromethyl-2-Hydroxy-Phenyl)-Ethanone is a versatile chlorinated aromatic ketone intermediate of significant importance in fine chemical synthesis. Its reactive chloromethyl and hydroxyl groups make it a valuable building block for constructing more complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzophenone or diaryl ether scaffolds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its chloromethyl group facilitates further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its rigid aromatic structure.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	1-(5-Chloromethyl-2-Hydroxy-Phenyl)-Ethanone
CAS No.	30787-43-0
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	5-(Chloromethyl)-2-hydroxyacetophenone; 2'-Hydroxy-5'-(chloromethyl)acetophenone; 1-(5-Chloromethyl-2-hydroxyphenyl)ethanone; 2-Acetyl-4-(chloromethyl)phenol; 4-Chloromethyl-2-hydroxyacetophenone
EINECS	Contact for details

Quality Control

Our 1-(5-Chloromethyl-2-Hydroxy-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to the presence of reactive functional groups, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.