Description

1-Cyanocyclobutanecarboxylic Acid is a versatile bifunctional organic building block featuring both a carboxylic acid and a nitrile group on a strained cyclobutane ring. This unique structure makes it a valuable intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients and fine chemicals. The compound, with CAS number 30491-91-9, enables the construction of conformationally constrained scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring a strained, four-membered ring system to modulate biological activity and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclobutane core can impart unique activity profiles.
• Material Science Research: Serves as a monomer or precursor for developing specialized polymers and advanced materials with tailored thermal or mechanical properties.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel chelating ligands and catalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and tools to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing high-value fine chemicals for clients.

Basic Information

Product Name	1-Cyanocyclobutanecarboxylic Acid
CAS No.	30491-91-9
Molecular Formula	C6H7NO2
Molecular Weight	125.13 g/mol
Synonyms	Cyclobutanecarboxylic acid, 1-cyano-; 1-Cyanocyclobutanecarboxylic acid; 1-Cyano-1-cyclobutanecarboxylic acid; 1-Carboxycyclobutanecarbonitrile; 1-Cyano-cyclobutanecarboxylic acid; 1-Cyanocyclobutane-1-carboxylic acid; (1-Cyanocyclobutyl)formic acid
EINECS	Contact for details

Quality Control

Our 1-Cyanocyclobutanecarboxylic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.