Description

(8α,9β,14β,23S,24R)-11β,23-Dihydroxy-24,25-Epoxy-5α-Dammar-13(17)-Ene-3,16-Dione is a high-purity, structurally defined dammarane-type triterpenoid derivative, valued for its role as a critical intermediate and reference standard in advanced pharmaceutical research and development. This compound is essential for scientists exploring novel therapeutic pathways, particularly in areas such as metabolic regulation and anti-inflammatory drug discovery. Its precise stereochemistry and functional groups make it a sought-after building block for medicinal chemistry and a key analyte in quality control for botanical extracts within the nutraceutical and pharmaceutical industries.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the semi-synthesis of novel drug candidates targeting metabolic diseases.
• Reference Standard: Used as a high-purity certified standard for the identification and quantification of related triterpenoids in complex matrices via HPLC and LC-MS.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new agents with potential anti-diabetic, hepatoprotective, or anti-inflammatory activity.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the standardization and authentication of ginseng and other botanicals containing dammarane sapogenins.
• Biochemical Research: Utilized as a tool compound to investigate biological pathways and enzyme interactions related to its pharmacological profile.
• Nutraceutical Quality Assurance: Essential for developing and validating analytical methods to ensure the potency and purity of herbal supplement ingredients.

Basic Information

Item	Details
Product Name	(8α,9β,14β,23S,24R)-11β,23-Dihydroxy-24,25-Epoxy-5α-Dammar-13(17)-Ene-3,16-Dione
CAS No.	30489-27-1
Molecular Formula	C30H46O6
Molecular Weight	502.69 g/mol
Synonyms	11β,23-Dihydroxy-24,25-epoxydammar-13(17)-ene-3,16-dione; 24,25-Epoxy-11β,23-dihydroxydammar-13(17)-en-3,16-dione; Dammar-13(17)-ene-3,16-dione, 11,23-dihydroxy-24,25-epoxy-, (8α,9β,14β,23S,24R)-; A key dammarane triterpenoid oxide; Ginsenoside related intermediate; Triterpenoid derivative
EINECS	Contact for details

Quality Control

Every batch of (8α,9β,14β,23S,24R)-11β,23-Dihydroxy-24,25-Epoxy-5α-Dammar-13(17)-Ene-3,16-Dione is manufactured under a strict quality management system. We employ advanced chromatographic techniques (HPLC, GC) and spectroscopic methods (NMR, MS) to ensure identity, purity, and stereochemical integrity. Comprehensive Certificates of Analysis (COA) detailing all specified parameters are provided with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation by atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.