Description

Grayanotoxin Vii is a potent diterpenoid neurotoxin belonging to the grayanotoxin family, identified by CAS No. 30460-59-4. This compound is of significant interest for its specific biological activity, primarily as a sodium channel modulator, making it a valuable tool for neurological and pharmacological research. It is essential for researchers and developers in the fields of neuroscience, toxicology, and natural product chemistry who require high-purity reference standards and active ingredients for investigative studies.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies of voltage-gated sodium channels and neuronal excitability.
• Toxicology Studies: Employed in the investigation of plant-derived toxins, poisoning mechanisms, and the development of detection methods.
• Neuroscience Tool Compound: Serves as a precise molecular tool to probe ion channel function and signal transduction pathways in cellular and animal models.
• Natural Product Isolation & Analysis: Acts as a key marker compound for the quality control and standardization of extracts from Ericaceae family plants (e.g., Rhododendron).
• Biochemical Assay Development: Utilized in the development and validation of high-throughput screening assays for channel activity or toxin identification.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in chemical ecology and plant defense mechanisms.

Basic Information

Product Name	Grayanotoxin Vii
CAS No.	30460-59-4
Molecular Formula	C22H36O7
Molecular Weight	412.52 g/mol
Synonyms	Grayanotoxin VII; Grayanotoxin 7; Acetylandromedol; Rhodojaponin VII; 3β,6β,14-Triacetoxy-1β,5β,10β,16-epoxygrayan-9(11)-ene; 1β,5β,10β,16-Diepoxy-3β,6β,14-triacetoxygrayan-9(11)-ene; Andromedotoxin derivative
EINECS	Contact for details

Quality Control

Our Grayanotoxin Vii is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous analytical standards, utilizing techniques such as HPLC, NMR, and MS for characterization, ensuring the material meets the exacting requirements of scientific investigation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.