Description

(14R)-Grayanotoxa-10(20),15-Diene-3β,5,6β,14-Tetrol 14-Acetate CAS NO 30460-58-3 is a specific diterpenoid compound belonging to the grayanotoxin family, known for its complex polycyclic structure and biological activity. This high-purity reference standard is critical for research and development in pharmacology and toxicology, where precise molecular characterization is required. It is primarily sought by analytical laboratories, academic research institutions, and pharmaceutical companies engaged in natural product chemistry, neurobiological studies, and the development of analytical methods.

Application

• Pharmacological Research Standard: Serves as a high-purity reference material for studying the biological activity and mechanism of action of grayanotoxin derivatives.
• Analytical Chemistry: Used as a certified reference standard (CRS) for the qualitative and quantitative analysis (e.g., via HPLC, LC-MS) of complex botanical extracts or biological samples.
• Toxicology Studies: Employed in research to understand the toxicological profile and metabolic pathways of grayanotoxins, which are relevant to food safety and forensic analysis.
• Natural Product Isolation & Synthesis: Acts as a key intermediate or target molecule for the synthesis, semi-synthesis, or structural elucidation of related diterpenoid compounds.
• Neuroscience Research: Utilized in electrophysiological studies to investigate its effects on sodium channels in nerve and muscle cells.
• Quality Control in Herbal Medicine: Functions as a marker compound for the standardization and quality assurance of herbal preparations that may contain grayanotoxin-producing plants.

Basic Information

Product Name	(14R)-Grayanotoxa-10(20),15-Diene-3β,5,6β,14-Tetrol 14-Acetate
CAS No.	30460-58-3
Molecular Formula	C22H34O6
Molecular Weight	394.50 g/mol
Synonyms	Grayanotoxin III 14-Acetate; 14-Acetoxygrayanotoxin III; (3β,5β,6β,14R)-Grayanotaxa-10(20),15-diene-3,5,6,14-tetrol 14-acetate; 14-O-Acetylgrayanotoxin III; Grayanotoxin III monoacetate; Acetylgrayanotoxin III; Grayanotoxin derivative 14-acetate
EINECS	Contact for details

Quality Control

Our (14R)-Grayanotoxa-10(20),15-Diene-3β,5,6β,14-Tetrol 14-Acetate is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the stringent requirements for research-grade reference materials. A detailed Certificate of Analysis (COA) providing batch-specific data on purity, identity, and impurities is supplied with every order to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or Certificate of Analysis. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.