Description

Methyl 3-Bromo-2,2-Dimethylpropanoate CAS NO 30452-00-7 is a versatile brominated ester building block, prized for its reactive bromomethyl group and sterically hindered structure. This compound is essential for introducing the 2,2-dimethylpropanoate moiety in complex molecular synthesis, enabling the creation of advanced intermediates. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as active pharmaceutical ingredient (API) synthesis and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sterically hindered ester functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromomethyl group facilitates further coupling reactions.
• Organic Synthesis Reagent: Serves as a versatile alkylating agent and precursor for generating more complex molecules in academic and industrial R&D laboratories.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors.

Basic Information

Product Name	Methyl 3-Bromo-2,2-Dimethylpropanoate
CAS No.	30452-00-7
Molecular Formula	C7H13BrO2
Molecular Weight	209.08 g/mol
Synonyms	3-Bromo-2,2-dimethylpropanoic Acid Methyl Ester; Methyl 3-Bromo-2,2-dimethylpropionate; 2,2-Dimethyl-3-bromopropionic Acid Methyl Ester; Neopentyl Bromoacetate Methyl Ester; Methyl β-Bromoneopentanoate; Bromoneopentanoic Acid Methyl Ester; 30452-00-7; Methyl ester of 3-bromo-2,2-dimethylpropanoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-2,2-Dimethylpropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.460
Density (20°C)	1.30 - 1.40 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.