Description

4-Bromo-2-Hydroxyacetophenone is a versatile brominated aromatic ketone that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a valuable building block for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with brominated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its reactive halogen site for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Useful building block for creating molecular probes and tags due to its modifiable bromine and ketone functionalities.
• Academic & R&D: A standard reagent in university and industrial research laboratories for method development and novel compound library synthesis.

Basic Information

Product Name	4-Bromo-2-Hydroxyacetophenone
CAS No.	30186-18-6
Molecular Formula	C8H7BrO2
Molecular Weight	215.04 g/mol
Synonyms	1-(4-Bromo-2-hydroxyphenyl)ethanone; 2'-Hydroxy-4'-bromoacetophenone; 4-Bromo-2'-hydroxyacetophenone; 4-Bromo-2-acetylphenol; 2-Acetyl-5-bromophenol; p-Bromo-o-hydroxyacetophenone; 4-Bromo-2-hydroxyphenyl methyl ketone
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Hydroxyacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.