Description

2-Butyl-1,3,2-Dioxaborinane CAS NO 30169-71-2 is a specialized organoboron compound belonging to the cyclic boronic ester class, valued for its role as a versatile synthetic intermediate and protecting group. Its primary commercial significance lies in enabling precise carbon-boron bond formation, a critical step in modern cross-coupling reactions for pharmaceutical and advanced material synthesis. This chemical is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries seeking efficient routes to complex molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures prevalent in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate: Serves as a protected boronic acid equivalent in the multi-step synthesis of drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in constructing novel herbicide and fungicide molecules that require specific boronic ester functionalities for bioactivity.
• Material Science & OLED Development: Employed as a building block for creating organic light-emitting diode (OLED) materials and other advanced polymers with tailored electronic properties.
• Chemical Research & Process Development: A valuable tool for medicinal and process chemists in academia and industry for developing new synthetic methodologies.
• As a Protecting Group: The cyclic dioxaborinane structure can temporarily mask boronic acid functionalities, improving stability and solubility during synthetic sequences.

Basic Information

Product Name	2-Butyl-1,3,2-Dioxaborinane
CAS No.	30169-71-2
Molecular Formula	C7H15BO2
Molecular Weight	142.00 g/mol
Synonyms	2-Butyl-1,3,2-dioxaborinane; 2-Butyl-1,3,2-dioxaborinane; 1,3,2-Dioxaborinane, 2-butyl-; 2-n-Butyl-1,3,2-dioxaborinane; Butylboronic acid, cyclic ester with 1,3-propanediol; Butylboronic acid 1,3-propanediol ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2-Butyl-1,3,2-Dioxaborinane is manufactured and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or NMR)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.