Description

1-Bromo-4-(Trifluoromethyl)Cyclohexane is a versatile halogenated cycloalkane building block prized for its unique combination of a reactive bromine substituent and a stable, lipophilic trifluoromethyl group. This compound is essential for introducing the cyclohexane scaffold and fluorine atoms into target molecules, significantly altering their physicochemical properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, particularly for introducing fluorinated cyclohexyl motifs to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and as a substrate for nucleophilic substitution to construct complex, fluorinated organic architectures.
• Polymer Modification: Utilized to incorporate halogenated and fluorinated segments into specialty polymers, altering characteristics like solvent resistance and surface energy.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science R&D, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-Bromo-4-(Trifluoromethyl)Cyclohexane
CAS No.	30129-20-5
Molecular Formula	C7H10BrF3
Molecular Weight	231.06 g/mol
Synonyms	4-(Trifluoromethyl)cyclohexyl bromide; (4-Trifluoromethylcyclohexyl)bromide; 1-Bromo-4-trifluoromethylcyclohexane; 4-Bromotrifluoromethylcyclohexane; trans/cis-1-Bromo-4-(trifluoromethyl)cyclohexane; Bromo(trifluoromethyl)cyclohexane
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Trifluoromethyl)Cyclohexane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by GC/HPLC), isomeric purity, and impurity profiles. Our quality commitment ensures the material meets the high standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Ratio (cis/trans)	Specified on COA
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.