Description

1-Bromo-4-tert-Butylbenzene is a versatile and high-purity brominated aromatic intermediate essential for advanced organic synthesis. Its value lies in the combination of a reactive bromine substituent with the sterically bulky and electron-donating tert-butyl group, making it a critical building block for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications ranging from catalyst ligands to liquid crystal precursors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a sterically hindered aryl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the tert-butylphenyl group enhances biological activity and stability.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing sophisticated phosphine and N-heterocyclic carbene (NHC) ligands used in cross-coupling and asymmetric catalysis.
• Liquid Crystal & OLED Materials: A fundamental building block for creating mesogenic cores and charge-transport materials in display and lighting technologies.
• Polymer Modification: Employed to introduce aromatic and bulky side chains into polymers to modify thermal properties, solubility, and rigidity.
• Organic Synthesis & Research: A valuable reagent for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create biaryl systems.

Basic Information

Product Name	1-Bromo-4-tert-Butylbenzene
CAS No.	3972-65-4
Molecular Formula	C10H13Br
Molecular Weight	213.12 g/mol
Synonyms	4-tert-Butylbromobenzene; p-tert-Butylbromobenzene; 1-Bromo-4-(1,1-dimethylethyl)benzene; 4-Bromo-tert-butylbenzene; 4-(tert-Butyl)phenyl bromide; p-(tert-Butyl)phenyl bromide; 4-tert-Butyl-1-bromobenzene; 3972-65-4
EINECS	223-603-5

Quality Control

Our 1-Bromo-4-tert-Butylbenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended long-term storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.