Description

3-tert-Butylbromobenzene is a high-purity brominated aromatic compound, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the combination of the electron-donating tert-butyl group and the reactive bromine atom, enabling precise functionalization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a sterically hindered aromatic moiety.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the tert-butylphenyl group contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Monomer: Employed in the production of advanced polymers and liquid crystals, where it modifies thermal and optical properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and Buchwald-Hartwig amination reactions to form biaryl and other carbon-heteroatom bonds.
• Organic Electronic Materials: A building block for hole-transport or emissive layers in OLEDs and other organic electronic devices.

Basic Information

Item	Details
Product Name	3-tert-Butylbromobenzene
CAS No.	3972-64-3
Molecular Formula	C10H13Br
Molecular Weight	213.12 g/mol
Synonyms	1-Bromo-3-tert-butylbenzene; m-tert-Butylbromobenzene; 3-tert-Butylphenyl bromide; (3-Bromophenyl)trimethylmethane; 3-(tert-Butyl)bromobenzene; m-(tert-Butyl)phenyl bromide; 3-tert-Butyl-1-bromobenzene; 3-Bromo-tert-butylbenzene
EINECS	223-603-8

Quality Control

Our 3-tert-Butylbromobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.