Description

1-tert-Butyl-4-Chlorobenzene is a versatile chlorinated aromatic compound, also known by its CAS number 3972-56-3. This chemical serves as a valuable intermediate and building block in advanced organic synthesis, prized for its stable tert-butyl group and reactive chlorine substituent. It is primarily used by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the production of active pharmaceutical ingredients (APIs), particularly for compounds requiring a sterically hindered aromatic moiety.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and other crop protection agents where the tert-butyl-chlorobenzene structure imparts specific biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science: Employed in the synthesis of monomers, polymers, and liquid crystals, contributing to thermal stability and specific material properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution to create more complex molecular architectures.
• Dye and Pigment Intermediate: Acts as a starting material in the production of certain dyes and organic pigments.

Basic Information

Product Name	1-tert-Butyl-4-Chlorobenzene
CAS No.	3972-56-3
Molecular Formula	C10H13Cl
Molecular Weight	168.66 g/mol
Synonyms	4-tert-Butylchlorobenzene; p-tert-Butylchlorobenzene; 1-Chloro-4-tert-butylbenzene; 4-(tert-Butyl)chlorobenzene; p-(tert-Butyl)chlorobenzene; 4-Chloro-1-tert-butylbenzene; 4-tert-Butylphenyl chloride; PTBC
EINECS	223-605-8

Quality Control

Our 1-tert-Butyl-4-Chlorobenzene is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the specifications required for sensitive synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and strong oxidizing agents. Recommended storage temperature is between 15°C and 25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.