Description

(R)-2-Hydroxy-2-Phenylbutyric Acid is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its utility as a key precursor for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic & Industrial Research: A valuable standard and reagent in methodological development for organic synthesis and stereochemistry studies.

Basic Information

Product Name	(R)-2-Hydroxy-2-Phenylbutyric Acid
CAS No.	3966-31-2
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	(R)-2-Phenyl-2-hydroxybutyric Acid; (R)-α-Hydroxy-α-phenylbutyric Acid; D-2-Hydroxy-2-phenylbutanoic Acid; (2R)-2-Hydroxy-2-phenylbutanoic Acid; (R)-2-Hydroxy-2-phenylbutanoic Acid; (R)-HPA; (R)-HPBA
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxy-2-Phenylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.