Description

Methyl 3-Chloro-4-Hydroxybenzoate is a versatile organic ester compound, serving as a crucial synthetic intermediate in advanced chemical manufacturing. Its value lies in the strategic positioning of its functional groups—a methyl ester, a chloro substituent, and a phenolic hydroxyl—which enable precise chemical modifications. This compound is essential for research chemists and industrial manufacturers in the pharmaceutical and agrochemical sectors who require high-purity building blocks for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated phenolic scaffold.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the chlorinated benzoate structure is integral to biological activity.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent in the synthesis of specialty polymers and liquid crystal materials for electronic displays.
• Organic Synthesis & Research: A valuable building block in academic and industrial R&D for constructing complex molecules via esterification, etherification, and cross-coupling reactions.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of certain azo dyes and high-performance pigments.
• UV Absorber & Stabilizer Precursor: Utilized in the development of additives for plastics and coatings that require light-stabilizing properties.

Basic Information

Product Name	Methyl 3-Chloro-4-Hydroxybenzoate
CAS No.	3964-57-6
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	3-Chloro-4-hydroxybenzoic acid methyl ester; Methyl 3-chloro-4-hydroxybenzoate; 4-Hydroxy-3-chlorobenzoic acid methyl ester; Benzoic acid, 3-chloro-4-hydroxy-, methyl ester; Methyl 4-hydroxy-3-chlorobenzoate; 3-Chloro-4-hydroxy methyl benzoate; Methyl (3-chloro-4-hydroxyphenyl)formate
EINECS	223-563-5

Quality Control

Our Methyl 3-Chloro-4-Hydroxybenzoate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of heat. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	128°C - 132°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.