Description

Ethyl 3,4-Dihydroxybenzoate is a versatile phenolic ester derivative of gallic acid, valued for its antioxidant and chelating properties. This compound is a key intermediate and functional additive in high-value synthesis and formulation processes. It is essential for manufacturers in the pharmaceutical, cosmetic, and specialty chemical industries seeking reliable, high-purity raw materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring catechol or polyphenolic structures for biological activity.
• Antioxidant Agent: Functions as a stabilizer in cosmetic and personal care formulations (e.g., creams, lotions) to prevent oxidation and extend shelf life.
• Food & Beverage Additive: Acts as a preservative and antioxidant in food-grade applications, helping to maintain product freshness and color.
• Chemical Synthesis Building Block: Serves as a precursor for producing more complex esters, polymers, and fine chemicals in organic chemistry.
• Research & Development: Utilized in biochemical and pharmacological research as a reference standard or tool compound for studying antioxidant mechanisms.
• Industrial Antioxidant: Incorporated into lubricants, plastics, and rubber products to inhibit oxidative degradation and material failure.

Basic Information

Product Name	Ethyl 3,4-Dihydroxybenzoate
CAS No.	3943-89-3
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	Ethyl Gallate; 3,4-Dihydroxybenzoic Acid Ethyl Ester; Ethyl Protocatechuate; Gallic Acid Ethyl Ester; Ethyl 3,4-Dihydroxybenzoate; Benzoic acid, 3,4-dihydroxy-, ethyl ester; NSC 404044; AI3-03110; EINECS 223-526-1
EINECS	223-526-1

Quality Control

Our Ethyl 3,4-Dihydroxybenzoate is manufactured under a strict quality management system. Each batch is tested to ensure it meets rigorous specifications for identity, purity, and composition. Certificates of Analysis (COA) documenting results for assay, related substances, and residual solvents are provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for industrial and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	140°C - 145°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.