Description

4-Toluenesulfonylacetic Acid is a versatile organic sulfonic acid derivative, serving as a key building block in advanced chemical synthesis. Its value lies in its dual functional groups, which enable its use as a reagent for introducing the tosyl (p-toluenesulfonyl) protecting group and as a precursor for more complex molecules. This compound is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with high purity and yield.

Application

• Pharmaceutical Intermediate: A crucial synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonyl or acetic acid functionalities.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators where the tosylacetic acid moiety is integral to biological activity.
• Organic Synthesis Reagent: Acts as a versatile reagent for alkylation, acylation, and as a precursor for generating other sulfonyl-based compounds in research laboratories.
• Polymer Chemistry: Employed as a monomer or modifying agent in the production of specialty polymers, including ion-exchange resins and materials with specific sulfonic acid properties.
• Chemical Research & Development: Serves as a standard or starting material in methodological studies and for the discovery of new catalytic processes or reaction pathways.
• Dye and Pigment Manufacturing: Utilized in the synthesis of sulfonated dyes and organic pigments that require specific solubility and color-fastness properties.

Basic Information

Product Name	4-Toluenesulfonylacetic Acid
CAS No.	3937-96-0
Molecular Formula	C9H10O4S
Molecular Weight	214.24 g/mol
Synonyms	p-Toluenesulfonylacetic Acid; (4-Methylphenyl)sulfonylacetic Acid; Tosylacetic Acid; 4-Methylbenzenesulfonylacetic Acid; TSAA; α-Toluenesulfonylacetic Acid; p-Tolylsulfonylacetic Acid; Benzenesulfonylacetic Acid, 4-methyl-
EINECS	223-519-1

Quality Control

Our 4-Toluenesulfonylacetic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product quality and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.