Description

2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Fluoride is a key fluorinated carbohydrate building block, specifically an acetyl-protected glycosyl fluoride donor. This compound is valued for its high reactivity and selectivity in glycosylation reactions, enabling the efficient synthesis of complex oligosaccharides and glycoconjugates. It is an essential intermediate for researchers and manufacturers in pharmaceutical development, carbohydrate chemistry, and the production of advanced bioactive molecules.

Application

• Glycosylation Reagent: A crucial donor molecule for the stereoselective synthesis of O-glycosidic bonds in oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Used in the research and production of glycosylated drugs, including certain antibiotics, antivirals, and anticancer agents.
• Carbohydrate Chemistry Research: Serves as a fundamental tool for academic and industrial research into new synthetic methodologies for complex sugars.
• Glycobiology Studies: Enables the construction of defined glycan structures for studying protein-carbohydrate interactions and biological recognition processes.
• Glycopolymer Synthesis: A monomer for creating synthetic polymers with pendant sugar moieties for material science and biomedical applications.
• Standards and Reference Material: Used as a high-purity analytical standard for quality control and method development in related chemical analyses.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Fluoride
CAS No.	3934-29-0
Molecular Formula	C₁₄H₁₉FO₉
Molecular Weight	350.29 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl fluoride; α-D-Glucopyranosyl fluoride, 2,3,4,6-tetraacetate; Tetra-O-acetyl-α-D-glucopyranosyl fluoride; 1-Fluoro-2,3,4,6-tetra-O-acetyl-α-D-glucopyranose; Ac₄GlcαF; α-Acetobromoglucose Fluoride Analog; Glc(Ac)₄αF; α-D-Glucopyranosyl fluoride tetraacetate
EINECS	223-515-4

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Fluoride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under inert conditions if prolonged exposure is anticipated to maintain optimal stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.