Description

1-Amino-3-Chloropropan-2-Ol is a versatile bifunctional organic compound featuring both amino and chlorohydrin functional groups, making it a valuable chiral building block in advanced synthesis. Its molecular structure is critical for introducing specific functionalities into target molecules, enabling the production of high-value intermediates. This compound is essential for research and development laboratories and industrial-scale manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-purity raw materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blocker drugs (e.g., propranolol, atenolol) and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Polymer & Resin Modifier: Used in the production of epoxy resins and polyurethane, where it acts as a curing agent or chain extender.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complex formation.
• Bioconjugation & Linker Chemistry: Utilized in proteomics and bioconjugation techniques to create cross-linkers and spacer arms.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and ring-opening reactions to introduce amino-alcohol motifs.

Basic Information

Product Name	1-Amino-3-Chloropropan-2-Ol
CAS No.	3920-12-5
Molecular Formula	C3H8ClNO
Molecular Weight	109.55 g/mol
Synonyms	3-Chloro-2-hydroxypropylamine; 1-Chloro-3-amino-2-propanol; 3-Chloro-1-amino-2-propanol; 2-Propanol, 1-amino-3-chloro-; (±)-1-Amino-3-chloro-2-propanol; DL-1-Amino-3-chloro-2-propanol; 3-Chloro-2-propanolamine; Amino chlorohydrin
EINECS	223-485-8

Quality Control

Our 1-Amino-3-Chloropropan-2-Ol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) documenting purity, enantiomeric excess (where applicable), and impurity profiles are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation (Optical Grade)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.