Description

5-Phenylisoxazole-3-Propionic Acid is a versatile heterocyclic carboxylic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique isoxazole core fused with a phenyl and propionic acid chain makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the isoxazole moiety.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers with unique thermal or optical properties.
• Ligand Synthesis: Employed in organometallic chemistry to create complex chelating ligands for catalysis.
• Chemical Biology Probe Development: Utilized as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Phenylisoxazole-3-Propionic Acid
CAS No.	3919-86-6
Molecular Formula	C12H11NO3
Molecular Weight	217.22 g/mol
Synonyms	3-(5-Phenylisoxazol-3-yl)propanoic Acid; 3-(5-Phenyl-1,2-oxazol-3-yl)propanoic Acid; 5-Phenyl-3-isoxazolepropionic Acid; 5-Phenylisoxazole-3-propanoic Acid; β-(5-Phenylisoxazol-3-yl)propionic Acid; NSC 163022
EINECS	Contact for details

Quality Control

Our 5-Phenylisoxazole-3-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	140 - 144 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.