Description

2-(Chloromethyl)-5-Methoxy-1,3,4-Thiadiazole is a versatile heterocyclic building block featuring a reactive chloromethyl group and a methoxy-substituted thiadiazole core. This compound is crucial for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate. It is primarily sought after by research chemists and process development teams in fine chemical manufacturing for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with thiadiazole-based pharmacophores for antimicrobial, anti-inflammatory, or anticancer activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the 1,3,4-thiadiazole ring system.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes due to its electrophilic chloromethyl group.
• Dye & Pigment Intermediate: Acts as a building block for synthesizing heterocyclic dyes and functional colorants.

Basic Information

Product Name	2-(Chloromethyl)-5-Methoxy-1,3,4-Thiadiazole
CAS No.	3914-44-1
Molecular Formula	C4H5ClN2OS
Molecular Weight	164.61 g/mol
Synonyms	5-Methoxy-2-(chloromethyl)-1,3,4-thiadiazole; 2-Chloromethyl-5-methoxy-1,3,4-thiadiazole; 5-Methoxy-2-chloromethyl-1,3,4-thiadiazole; Methoxy(chloromethyl)thiadiazole; 1,3,4-Thiadiazole, 2-(chloromethyl)-5-methoxy-; CMTD
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)-5-Methoxy-1,3,4-Thiadiazole is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.