Description

4-Fluoro-3-Nitrobenzenesulphonic Acid is a versatile aromatic sulfonic acid derivative, serving as a key fluorinated and nitrated building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the electron-withdrawing nitro and sulfonic acid groups, which facilitate a range of substitution and coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorine for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing sulfonated azo dyes and other complex colorants, contributing to color fastness and solubility.
• Liquid Crystal & Electronic Chemicals: Serves as a building block for fluorinated compounds used in liquid crystal displays (LCDs) and other electronic materials.
• Polymer Modification: Employed to introduce sulfonic acid groups into polymer chains, enhancing properties like hydrophilicity or ion-exchange capacity.
• Chemical Research & Development: A valuable reagent for exploring new fluorination pathways and creating libraries of novel chemical entities for screening.

Basic Information

Item	Details
Product Name	4-Fluoro-3-Nitrobenzenesulphonic Acid
CAS No.	3888-84-4
Molecular Formula	C6H4FNO5S
Molecular Weight	221.16 g/mol
Synonyms	4-Fluoro-3-nitrobenzenesulfonic acid; 3-Nitro-4-fluorobenzenesulfonic acid; Benzenesulfonic acid, 4-fluoro-3-nitro-; 4-Fluoro-3-nitrobenzene-1-sulfonic acid; 3-Nitro-4-fluorophenylsulfonic acid; 4-Fluoro-3-nitrophenylsulfonic acid; 3888-84-4; 4-Fluoro-3-nitrobenzenesulphonate
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-Nitrobenzenesulphonic Acid is produced and tested under a strict quality management system to ensure consistency and reliability for industrial and research applications. We provide comprehensive analytical data, including purity by HPLC, identity confirmation (IR, NMR), and control of key impurities. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept sealed to prevent absorption of atmospheric moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.