Description

1-Hexadecanol-1-14C is a carbon-14 labeled isotopologue of cetyl alcohol, a long-chain primary fatty alcohol. This labeled compound is essential for precise metabolic and pharmacokinetic studies, providing a reliable tracer for tracking the fate of cetyl alcohol derivatives in biological and chemical systems. It is a critical tool for researchers and formulators in the pharmaceutical, cosmetic, and chemical synthesis industries who require definitive data on absorption, distribution, and degradation pathways.

Application

• Tracer Studies in Pharmaceutical R&D: Used as a radiolabeled standard in ADME (Absorption, Distribution, Metabolism, Excretion) studies for drug candidates derived from fatty alcohols.
• Metabolic Pathway Analysis: Enables detailed investigation of lipid metabolism and surfactant biodegradation in environmental and biological research.
• Cosmetic & Personal Care Formulation Research: Tracks the penetration, stability, and metabolic processing of emollients and thickeners like cetyl alcohol in topical formulations.
• Chemical Synthesis Mechanism Elucidation: Serves as a labeled starting material or intermediate to study reaction mechanisms and catalyst efficiency in organic synthesis.
• Quality Control & Reference Standard: Acts as an internal standard in advanced analytical techniques (e.g., LC-MS, GC-MS) for quantifying unlabeled cetyl alcohol in complex matrices.

Basic Information

Product Name	1-Hexadecanol-1-14C
CAS No.	3877-54-1
Molecular Formula	C1512C14CH3OH or C16H34O (with 14C at position 1)
Molecular Weight	~242.45 g/mol (exact mass depends on specific activity)
Synonyms	[1-14C]Cetyl Alcohol; 1-Tetradecanol-1-14C (common misnomer); Hexadecan-1-ol-1-14C; Radiolabeled Cetyl Alcohol; C16 Alcohol-1-14C; Palmityl Alcohol-1-14C; n-Hexadecyl Alcohol-1-14C
EINECS	For the unlabeled compound: 223-395-2

Quality Control

Every batch of 1-Hexadecanol-1-14C is manufactured and analyzed under strict quality protocols to ensure identity, purity, and specific activity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing radiochemical purity (typically >97% by HPLC), chemical purity, and specific activity. Our quality systems support research requiring traceable and reliable radiolabeled materials.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a dedicated, appropriately shielded facility for radioactive materials. Ensure compliance with all local and international regulations for the handling and storage of radiochemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (GC/HPLC)	≥ 98%
Specific Activity	Contact for details (mCi/mmol)
Solvent (if supplied in solution)	Specified on label

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.