Description

1,6-Anhydro-2-o-p-Toluenesulfonyl-B-D-Glucopyranose is a key anhydro sugar derivative, specifically a tosylated glucopyranose, widely utilized as a versatile synthetic intermediate in carbohydrate chemistry. Its primary value lies in its role as a protected glycosyl donor or acceptor, enabling the controlled synthesis of complex oligosaccharides and glycoconjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors, particularly for developing novel glycosidase inhibitors, prodrugs, and advanced materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel glycosidase inhibitors, antiviral agents, and carbohydrate-based drugs.
• Glycochemistry Research: Serves as a protected monosaccharide unit for the controlled, stepwise construction of complex oligosaccharides and glycoconjugates.
• Prodrug Development: Used to create targeted prodrugs where the tosyl group facilitates specific enzymatic cleavage for controlled drug release.
• Agrochemical Synthesis: Intermediate in the production of specialized surfactants, adjuvants, or active ingredients with sugar-based motifs.
• Material Science: Precursor for synthesizing functionalized polymers, hydrogels, or dendritic materials with tailored biological properties.
• Biochemical Tool Development: Employed in the design and synthesis of activity-based probes and inhibitors for studying glycosidase enzymes.

Basic Information

Product Name	1,6-Anhydro-2-o-p-Toluenesulfonyl-B-D-Glucopyranose
CAS No.	3868-05-1
Molecular Formula	C₁₃H₁₆O₇S
Molecular Weight	316.33 g/mol
Synonyms	1,6-Anhydro-2-O-tosyl-β-D-glucopyranose; 2-O-Tosyl-1,6-anhydro-β-D-glucopyranose; Levoglucosan 2-tosylate; 1,6-Anhydro-2-O-(p-tolylsulfonyl)-β-D-glucopyranose; 2-O-p-Toluenesulfonyl-1,6-anhydro-β-D-glucopyranose; β-D-Glucopyranose, 1,6-anhydro-2-O-(4-methylphenyl)sulfonyl-; Tosyl levoglucosan
EINECS	Contact for details

Quality Control

Our 1,6-Anhydro-2-o-p-Toluenesulfonyl-B-D-Glucopyranose is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.