Description

Cyclobutanecarboxylic Acid, 3,3-Dimethyl-, Methyl Ester is a high-purity, specialized organic ester building block valued for its unique sterically hindered cyclobutane structure. This compound is essential for advanced organic synthesis, particularly in pharmaceutical research and fine chemical manufacturing, where it serves as a key intermediate. It is primarily sought by R&D chemists and process development scientists in the life sciences, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring constrained, three-dimensional frameworks.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclobutane ring can impart favorable biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Investigated as a monomer or additive for producing polymers with unique thermal and mechanical properties due to its rigid, aliphatic structure.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex aroma chemicals with novel olfactory profiles.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3,3-Dimethyl-, Methyl Ester
CAS No.	3854-83-9
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	Methyl 3,3-Dimethylcyclobutanecarboxylate; 3,3-Dimethylcyclobutanecarboxylic Acid Methyl Ester; 3,3-Dimethylcyclobutane-1-carboxylic Acid Methyl Ester; Methyl 3,3-Dimethyl-1-cyclobutanecarboxylate; Cyclobutanecarboxylic Acid, 3,3-Dimethyl-, Methyl Ester; 3854-83-9; Methyl 3,3-dimethylcyclobutanecarboxylate
EINECS	223-376-6

Quality Control

Our Cyclobutanecarboxylic Acid, 3,3-Dimethyl-, Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Gravity (20°C)	0.950 - 0.980
Refractive Index (n20D)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.