Description

12-Fluoro-6-Dodecanone is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a fluorine atom at the 12-position and a carbonyl group at the 6-position of a dodecane chain, makes it a valuable intermediate for introducing fluorinated segments into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries, where it is used to modulate the physicochemical properties, metabolic stability, and bioavailability of new chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs, leveraging fluorine's ability to enhance membrane permeability and metabolic resistance.
• Agrochemical Research: Used in developing novel fluorinated pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence profiles.
• Material Science Precursor: Serves as a building block for fluorinated surfactants, lubricants, and specialty polymers that require specific surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and condensation reactions to construct complex fluoroorganic molecules for various research applications.
• Liquid Crystal & Display Technology: A potential intermediate in the synthesis of fluorinated liquid crystal compounds used in advanced display panels.

Basic Information

Product Name	12-Fluoro-6-Dodecanone
CAS No.	3833-07-6
Molecular Formula	C₁₂H₂₃FO
Molecular Weight	202.31 g/mol
Synonyms	6-Dodecanone, 12-fluoro-; 12-Fluorododecan-6-one; 1-Fluoro-6-dodecanone; 6-Oxododecyl fluoride; 12-Fluorolaurone; ω-Fluorolaurone; 6-Keto-1-fluorododecane
EINECS	Contact for details

Quality Control

Every batch of 12-Fluoro-6-Dodecanone is produced and tested under a strict quality management system to ensure high purity and consistency. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and sources of fluoride ions. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.