Description

Bromodifluoroacetyl Chloride is a highly reactive and versatile organofluorine building block essential for introducing the bromodifluoroacetyl moiety into target molecules. This compound matters for its critical role in the synthesis of complex fluorinated intermediates, which are increasingly valuable in modern pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Synthesis: Used in the production of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Employed in the creation of specialty polymers and surface modifiers to impart unique hydrophobic or oleophobic properties.
• Organic Synthesis Reagent: Acts as a versatile electrophile for Friedel-Crafts acylation and other reactions to construct complex organic frameworks.
• Fluorinated Liquid Crystal Precursor: Serves as a starting material for synthesizing fluorinated components used in display technologies.
• PET Tracer Development: Potential use in radiochemistry for creating positron emission tomography (PET) imaging agents.

Basic Information

Product Name	Bromodifluoroacetyl Chloride
CAS No.	3832-48-2
Molecular Formula	C2BrClF2O
Molecular Weight	193.38 g/mol
Synonyms	Bromodifluoroacetic Acid Chloride; 2-Bromo-2,2-difluoroacetyl Chloride; Bromodifluoroacetyl Chloride; Difluorobromoacetyl Chloride; α-Bromo-α,α-difluoroacetyl Chloride; Bromodifluoroethanoyl Chloride; Bromodifluoroacetic Chloride; Acetyl chloride, 2-bromo-2,2-difluoro-
EINECS	223-340-7

Quality Control

Our Bromodifluoroacetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.