Description

n-Piperidinotrimethylsilane is a specialized organosilicon compound that serves as a versatile reagent in advanced organic synthesis. Its value lies in its ability to act as a silylating agent and a protected piperidine precursor, facilitating the synthesis of complex molecules with high efficiency. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of piperidine-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the piperidine moiety is a critical functional group.
• Silylating Agent: Protects hydroxyl and amine groups in complex multi-step organic syntheses, particularly in peptide and nucleotide chemistry.
• Material Science Research: Employed in the development of novel silicon-based polymers, coatings, and surface-modifying agents.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Laboratory Reagent: A valuable tool for academic and industrial R&D in methodology development and exploratory chemistry.

Basic Information

Product Name	n-Piperidinotrimethylsilane
CAS No.	3768-56-7
Molecular Formula	C8H21NSi
Molecular Weight	159.35 g/mol
Synonyms	1-(Trimethylsilyl)piperidine; N-Trimethylsilylpiperidine; Piperidine, 1-(trimethylsilyl)-; N-(Trimethylsilyl)piperidine; Trimethyl(piperidino)silane; N-Piperidyltrimethylsilane; N-TMS-piperidine; NSC 163083
EINECS	223-193-1

Quality Control

Our n-Piperidinotrimethylsilane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for research and development applications under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.