Description

(R)-(+)-1,2-Epoxybutane is a high-purity chiral epoxide, a valuable building block in asymmetric synthesis. Its enantiomeric purity makes it a critical intermediate for producing optically active pharmaceuticals and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce chiral centers with high stereoselectivity.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the production of enantiomerically pure active pharmaceutical ingredients (APIs), such as β-blockers and other cardiovascular drugs.
• Agrochemical Production: Used in the synthesis of chiral herbicides, fungicides, and pesticides where specific stereochemistry is required for biological activity.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical & Flavor/Fragrance Intermediates: Employed in the creation of complex, optically active molecules for flavors, fragrances, and advanced materials.
• Polymer Modification: Can be used to introduce reactive epoxide groups into polymer chains for cross-linking or to create functional materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process research.

Basic Information

Product Name	(R)-(+)-1,2-Epoxybutane
CAS No.	3760-95-0
Molecular Formula	C4H8O
Molecular Weight	72.11 g/mol
Synonyms	(R)-(+)-Butylene Oxide; (R)-1,2-Butylene Oxide; (R)-1,2-Epoxybutane; (R)-Ethyloxirane; (+)-(R)-1,2-Epoxybutane; (2R)-2-Ethyloxirane; (R)-Butane-1,2-epoxide; (R)-1,2-Butene oxide
EINECS	223-189-1

Quality Control

Our (R)-(+)-1,2-Epoxybutane is produced under strict quality management systems. Each batch is analyzed to ensure high chemical and enantiomeric purity, meeting the stringent requirements for chiral intermediates. Comprehensive testing includes assay, enantiomeric excess (ee) determination, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (ee) (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.