Description

3-(Dimethoxyphosphinyloxy)-2-Butenoic Acid 3-Nitrobenzyl Ester is a specialized organophosphorus compound with a unique molecular structure combining a phosphonate ester and a nitrobenzyl-protected carboxylic acid. This chemical matters as a critical synthetic intermediate and protecting group reagent, enabling precise chemical transformations in advanced organic synthesis. It is primarily needed by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and complex fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protecting group reagent for carboxylic acids during solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Acts as a precursor in the development of novel organophosphate-based insecticides and herbicides.
• Material Science: Employed in the synthesis of functional monomers and polymers with specific photochemical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and mechanism.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	3-(Dimethoxyphosphinyloxy)-2-Butenoic Acid 3-Nitrobenzyl Ester
CAS No.	3734-58-5
Molecular Formula	C₁₃H₁₆NO₇P
Molecular Weight	329.24 g/mol
Synonyms	3-Nitrobenzyl 3-(Dimethoxyphosphoryloxy)but-2-enoate; 2-Butenoic acid, 3-(dimethoxyphosphinyloxy)-, 3-nitrobenzyl ester; 3-Nitrobenzyl (E)-3-(dimethoxyphosphoryloxy)but-2-enoate; 3-Nitrobenzyl 2-(dimethoxyphosphoryloxy)crotonate; Phosphonooxycrotonic Acid 3-Nitrobenzyl Ester; DMOP-ONB Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-(Dimethoxyphosphinyloxy)-2-Butenoic Acid 3-Nitrobenzyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.