Description

1-(Ethoxycarbonyl)Cyclopropanecarboxylic Acid is a versatile cyclopropane derivative that serves as a critical bifunctional building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and an ester group on a strained three-membered ring, enables the construction of complex molecular architectures with high precision. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce the pharmacologically valuable cyclopropane moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane rings for enhanced metabolic stability and biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the cyclopropane group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with unique thermal or mechanical properties derived from the strained ring system.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	1-(Ethoxycarbonyl)Cyclopropanecarboxylic Acid
CAS No.	3697-66-3
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	Cyclopropane-1,1-dicarboxylic acid monoethyl ester; Ethyl 1-carboxycyclopropanecarboxylate; 1-Carboxycyclopropanecarboxylic acid ethyl ester; Monoethyl cyclopropane-1,1-dicarboxylate; Cyclopropanedicarboxylic acid, monoethyl ester; Ethyl hydrogen cyclopropane-1,1-dicarboxylate; 1-Ethoxycarbonylcyclopropanecarboxylic acid
EINECS	223-045-1

Quality Control

Our 1-(Ethoxycarbonyl)Cyclopropanecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.