Description

11α,12α-Epoxy-3β,13-Dihydroxy-30-Norolean-20(29)-En-28-Oic Acid γ-Lactone is a high-purity, specialized triterpenoid derivative with a complex, functionalized oleanane-type skeleton. This compound matters as a critical advanced intermediate or reference standard for pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors working on anti-inflammatory, antiviral, or anticancer agents.

Application

• Pharmaceutical Intermediate: Key building block for the semi-synthesis of novel pentacyclic triterpenoid analogs with potential therapeutic activity.
• Reference Standard: High-purity material for analytical method development, qualification, and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies targeting various biological pathways.
• Natural Product Derivative Synthesis: Used to create modified derivatives of oleanolic acid and related natural products for enhanced bioavailability or efficacy.
• Biochemical Research: Probe compound for investigating enzyme interactions or cellular mechanisms related to triterpenoid metabolism.

Basic Information

Product Name	11α,12α-Epoxy-3β,13-Dihydroxy-30-Norolean-20(29)-En-28-Oic Acid γ-Lactone
CAS No.	3676-33-3
Molecular Formula	C₂₉H₄₀O₅
Molecular Weight	468.63 g/mol
Synonyms	11α,12α-Epoxy-3β,13-dihydroxy-30-norolean-20(29)-en-28-oic acid γ-lactone; 3β,13-Dihydroxy-11α,12α-epoxy-30-norolean-20(29)-en-28-oic acid γ-lactone; 30-Norolean-20(29)-en-28-oic acid, 11α,12α-epoxy-3β,13-dihydroxy-, γ-lactone; (3β,11α,12α)-11,12-Epoxy-3,13-dihydroxy-30-norolean-20(29)-en-28-oic acid γ-lactone; Oleanane triterpenoid lactone derivative.
EINECS	Contact for details

Quality Control

Our 11α,12α-Epoxy-3β,13-Dihydroxy-30-Norolean-20(29)-En-28-Oic Acid γ-Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP guidelines. Specifications can be aligned with pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.