Description

(1Ar,5Aα,8Aβ,8Bα)-1A,3,3A,4,5,5A,6,8A,8B,8C-Decahydro-3β-Hydroxy-3Aβ,8Cβ-Dimethyl-6-Methyleneoxireno[7,8]Naphtho[1,2-B]Furan-7(2H)-One is a complex, high-purity diterpenoid lactone derivative with a unique oxireno-naphthofuranone structure. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile scaffold for synthetic organic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its intricate polycyclic framework.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex diterpenoid natural products.
• Biochemical Research: Investigated for its potential biological activity and as a tool compound in enzymatic and receptor binding studies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical purity and complex molecular architecture.

Basic Information

Product Name	(1Ar,5Aα,8Aβ,8Bα)-1A,3,3A,4,5,5A,6,8A,8B,8C-Decahydro-3β-Hydroxy-3Aβ,8Cβ-Dimethyl-6-Methyleneoxireno[7,8]Naphtho[1,2-B]Furan-7(2H)-One
CAS No.	3668-04-0
Molecular Formula	C20H26O4
Molecular Weight	330.42 g/mol
Synonyms	6-Methyleneoxireno[7,8]naphtho[1,2-b]furan-7(2H)-one, 1A,3,3A,4,5,5A,6,8A,8B,8C-decahydro-3-hydroxy-3A,8C-dimethyl-, (1Ar,5Aα,8Aβ,8Bα)-; 6-Methylene-4,5-seco-19-nor-4,5-secoandrostane derivative; Androstane-6-methyleneoxireno derivative; 4,5-Seco-6-methylene-19-norandrostane lactone; A complex diterpenoid oxireno-lactone.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and cGMP-grade manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.