Description

4-(2-Methylphenyl)Tetrahydropyran-4-Carbonitrile, 97+% is a high-purity, versatile organic building block featuring a tetrahydropyran ring fused with an ortho-methylphenyl nitrile moiety. This compound is valued for its role as a key chiral intermediate and scaffold in advanced synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure.
• Ligand and Catalyst Development: Acts as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for specialty polymers with tailored thermal or optical properties.
• Academic & Industrial R&D: Employed in exploratory organic synthesis for method development and library synthesis in combinatorial chemistry.

Basic Information

Product Name	4-(2-Methylphenyl)Tetrahydropyran-4-Carbonitrile, 97+%
CAS No.	3648-76-8
Molecular Formula	C13H15NO
Molecular Weight	201.27 g/mol
Synonyms	4-(2-Methylphenyl)-4-cyanotetrahydropyran; 4-(o-Tolyl)tetrahydropyran-4-carbonitrile; 2-Methyl-α-(tetrahydro-4-pyranyl)benzenecarbonitrile; 4-Cyano-4-(2-methylphenyl)tetrahydropyran; 3648-76-8; Tetrahydropyran-4-carbonitrile, 4-(2-methylphenyl)-; 4-(2-Methylphenyl)tetrahydropyran-4-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Methylphenyl)Tetrahydropyran-4-Carbonitrile is manufactured and tested under a strict quality management system. We guarantee a minimum purity of 97%, verified by advanced analytical techniques including HPLC, GC, and NMR spectroscopy. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.