Description

Methyl 4-Acetylbenzoate is a high-purity aromatic ester derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, containing both an ester and a ketone group, which allows for selective transformations and the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzoate or acetophenone motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators where its aromatic core provides structural stability.
• Liquid Crystal & OLED Materials: Serves as a starting material for synthesizing advanced organic electronic materials and liquid crystal compounds.
• Organic Synthesis & Research: A versatile reagent for Friedel-Crafts acylation, esterification, and condensation reactions in academic and industrial R&D laboratories.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of complex organic dyes and pigments, contributing to colorant properties.
• Polymer Modification: Can be used to introduce functional groups into polymer chains for specialty plastics and coatings with enhanced properties.

Basic Information

Product Name	Methyl 4-Acetylbenzoate
CAS No.	3609-53-8
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	Methyl p-acetylbenzoate; 4-Acetylbenzoic Acid Methyl Ester; p-Acetyl Methyl Benzoate; Methyl 4-Acetylbenzenecarboxylate; Benzoic acid, 4-acetyl-, methyl ester; Methyl (4-acetylphenyl)formate; Methyl p-formylacetophenone (less common)
EINECS	222-787-4

Quality Control

Every batch of Methyl 4-Acetylbenzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.