Description

3-(Nitromethyl)-2-Benzofuran-1(3H)-One is a specialized organic compound featuring a benzofuranone core functionalized with a nitromethyl group. This unique structure makes it a valuable versatile synthetic intermediate and building block for the development of more complex molecules. It is primarily sought after by pharmaceutical research and fine chemical synthesis sectors for constructing novel heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive nitro and carbonyl functionalities.
• Organic Synthesis Building Block: Employed in cyclization reactions, Michael additions, and other transformations to create complex heterocyclic frameworks.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers and advanced organic materials.
• Dye and Pigment Synthesis: Serves as an intermediate for producing specialized colorants and functional dyes.

Basic Information

Product Name	3-(Nitromethyl)-2-Benzofuran-1(3H)-One
CAS No.	3598-68-3
Molecular Formula	C9H7NO4
Molecular Weight	193.16 g/mol
Synonyms	3-(Nitromethyl)-1(3H)-isobenzofuranone; 3-(Nitromethyl)phthalide; 1(3H)-Isobenzofuranone, 3-(nitromethyl)-; 3-Nitromethylphthalide; Phthalide, 3-nitromethyl-; 3-(Nitromethyl)-2-benzofuran-1-one; 3-Nitromethyl-1(3H)-isobenzofuranone
EINECS	Contact for details

Quality Control

Our production of 3-(Nitromethyl)-2-Benzofuran-1(3H)-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Every lot is characterized and tested using advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as an organic compound that is easily oxidized, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.