Description

4-(Phthalimidyl)Butanal is a high-purity, versatile chemical intermediate featuring a reactive aldehyde group attached to a phthalimide-protected amine moiety. This compound is valued for its role in the synthesis of complex molecules, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing nitrogen-containing heterocycles and functionalized building blocks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing γ-aminobutyric acid (GABA) analogs or other nitrogen heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for the preparation of aldehydes, amines, and protected amino aldehydes via further chemical transformations.
• Ligand and Catalyst Development: Useful precursor for synthesizing novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Potential use in linker chemistry for bioconjugates due to its reactive aldehyde group, which can form Schiff bases with amines.

Basic Information

Product Name	4-(Phthalimidyl)Butanal
CAS No.	3598-60-5
Molecular Formula	C₁₂H₁₁NO₃
Molecular Weight	217.22 g/mol
Synonyms	4-(1,3-Dioxoisoindolin-2-yl)butanal; 2-(4-Oxobutyl)isoindoline-1,3-dione; 4-Phthalimidobutyraldehyde; N-(3-Formylpropyl)phthalimide; 4-Phthalimido-1-butanal; 4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)butanal; 4-Phthalimidobutanal; 4-(Phthalimido)butyraldehyde
EINECS	Contact for details

Quality Control

Our 4-(Phthalimidyl)Butanal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.