Description

Tetraphenyl Phosphonium Fluoride is a versatile organophosphonium salt widely used as a phase-transfer catalyst and fluorinating agent in organic synthesis. Its primary commercial value lies in its ability to facilitate reactions between reagents in immiscible phases and to introduce fluorine atoms into complex molecules. This compound is particularly essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates and specialized catalysts.

Application

• Phase-Transfer Catalyst (PTC): Enables reactions between ionic reagents in aqueous phases and organic substrates in organic solvents, crucial for alkylation, esterification, and polymerization processes.
• Fluorination Reagent: Used as a source of fluoride ions (F⁻) for nucleophilic fluorination reactions to synthesize fluoroorganic compounds, which are key in drug development and material science.
• Polymerization Initiator/Catalyst: Facilitates the synthesis of specific polymers and resins, where controlled initiation is required.
• Pharmaceutical Intermediate: Serves as a building block or catalyst in the multistep synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorine.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, pesticides, and plant growth regulators that incorporate fluorine for enhanced efficacy and stability.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve stability and performance at high voltages.
• Organic Synthesis Reagent: A valuable tool in research laboratories for various organic transformations, including desilylation and the generation of reactive intermediates.

Basic Information

Product Name	Tetraphenyl Phosphonium Fluoride
CAS No.	3587-05-1
Molecular Formula	C24H20FP
Molecular Weight	358.39 g/mol
Synonyms	TPPF; Tetraphenylphosphonium Fluoride; Fluorotetraphenylphosphorane; Phosphonium, tetraphenyl-, fluoride (1:1); Tetraphenylphosphoranium Fluoride; TPP-F; [Ph4P]F
EINECS	Contact for details

Quality Control

Our Tetraphenyl Phosphonium Fluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Specifications can be tailored to meet specific research or cGMP guidelines for pharmaceutical intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.