Description

2-Bromo-1,3,2-Benzodioxaphosphole is a specialized organophosphorus compound that serves as a versatile building block in advanced chemical synthesis. Its unique heterocyclic structure, featuring a phosphorus atom within a fused ring system, makes it a valuable reagent for introducing phosphorus-containing functional groups. This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures. Its reactivity profile enables key transformations in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, insecticides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a starting material for creating novel phosphorus-based ligands used in homogeneous catalysis (e.g., cross-coupling reactions).
• Flame Retardant Research: Investigated as a potential intermediate for developing new, more efficient organophosphorus flame retardants.
• Material Science: Employed in the synthesis of specialty polymers and functional materials with tailored properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways involving phosphorylation.

Basic Information

Product Name	2-Bromo-1,3,2-Benzodioxaphosphole
CAS No.	3583-02-6
Molecular Formula	C6H4BrO2P
Molecular Weight	218.97 g/mol
Synonyms	2-Bromo-1,3,2-benzodioxaphosphole; 2-Bromobenzo[d][1,3,2]dioxaphosphole; 2-Bromo-2H-1,3,2-benzodioxaphosphole; Benzo-1,3,2-dioxaphosphole, 2-bromo-; 2-Bromobenzo-1,3,2-dioxaphosphole; 2-Bromo-2H-benzo[d][1,3,2]dioxaphosphole; 2-Bromophenoxyphosphinous bromide cyclic ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,3,2-Benzodioxaphosphole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles. We are committed to supplying material that meets the stringent requirements of research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.