Description

(1R)-7β-Ethenyl-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ,7-Trimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex steroidal-like structure. This compound is critical for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology research. It serves as a key building block for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of steroidal drugs and hormone analogs.
• Medicinal Chemistry Research: Used as a scaffold for the design and development of new chemical entities (NCEs) targeting specific biological pathways.
• Process Development & Scale-up: Serves as a reference standard and starting material for optimizing manufacturing routes in GMP environments.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and metabolic pathways.
• Bioconjugation & Prodrug Synthesis: The carboxylic acid methyl ester group provides a handle for further chemical modification and linkage to other molecules.

Basic Information

Product Name	(1R)-7β-Ethenyl-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ,7-Trimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester
CAS No.	3582-26-1
Molecular Formula	C21H32O2
Molecular Weight	316.48 g/mol
Synonyms	Methyl (1R,4aS,10aα)-7-Ethenyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylate; 7-Vinyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylic Acid Methyl Ester (1R,4aS,10aα)-; (1R,4aS,10aα)-7-Ethenyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylic Acid Methyl Ester; A key intermediate for steroidal synthesis.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects requiring compliance with ICH guidelines and can tailor specifications to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.