Description

(-)-Pemoline is a chiral organic compound belonging to the oxazolidinone class, known for its specific stereochemistry. This enantiomerically pure material is of significant interest for research and development in neuropharmacology and medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers requiring high-purity chiral building blocks for synthesis and biological evaluation.

Application

• Pharmaceutical Research & Development: As a key chiral intermediate or reference standard in the synthesis and study of central nervous system (CNS) active compounds.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to investigate the pharmacological profile of specific enantiomers.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Employed in in-vitro studies to explore mechanisms of action related to dopaminergic pathways.
• Fine Chemical Synthesis: Acts as a specialized chiral precursor for the synthesis of more complex, biologically relevant molecules.

Basic Information

Product Name	(-)-Pemoline
CAS No.	3469-02-1
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	(-)-2-Amino-5-phenyl-2-oxazolin-4-one; Levopemoline; (4S)-2-Amino-5-phenyl-4,5-dihydro-1,3-oxazol-4-one; Pemoline (levo-isomer); 2-Imino-5-phenyl-4-oxazolidinone (enantiomer); Phenylpseudohydantoin; Cylert (stereoisomer); Kethamed; Tradon; Volital (stereoisomer)
EINECS	222-422-4

Quality Control

Our (-)-Pemoline is manufactured under controlled conditions to ensure high enantiomeric purity and chemical integrity. Quality is assured through rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with each batch to support your research and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.