Description

2-Mercapto-6-Methylnicotinonitrile is a versatile heterocyclic building block featuring both a nitrile and a thiol functional group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by researchers and manufacturers in the life sciences sector for constructing novel drug candidates, especially those targeting central nervous system disorders and other therapeutic areas. Its unique structure allows for further functionalization, making it a critical component in modern medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of nicotinic acid receptor modulators and other neuroactive compounds.
• Agrochemical Research: Used in the discovery and synthesis of novel pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science Precursor: Serves as a starting material for the creation of specialized ligands, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Synthesis Reagent: Employed in organic synthesis for constructing complex pyridine and pyrimidine derivatives through its reactive thiol and nitrile groups.
• Bioconjugation Chemistry: The thiol group allows for use in bioconjugation techniques, linking molecules to proteins or other biomolecules for diagnostic or therapeutic purposes.

Basic Information

Product Name	2-Mercapto-6-Methylnicotinonitrile
CAS No.	3395-04-8
Molecular Formula	C7H6N2S
Molecular Weight	150.20 g/mol
Synonyms	6-Methyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile; 2-Mercapto-6-methyl-3-cyanopyridine; 2-Thio-6-methylnicotinonitrile; 3-Cyano-6-methyl-2(1H)-pyridinethione; 2-Mercapto-6-methylnicotinamide nitrile; 6-Methyl-2-mercaptonicotinonitrile; 2-Sulfanyl-6-methylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Mercapto-6-Methylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.